For biological research we have a number of AFMs integrated with optical microscopes to be able to use both techniques simultaneously. This is a useful combination as the techniques give different information on the sample. The AFM can be used for high resolution images of surfaces as well as for mechanical characterization or manipulation of samples while optical microscopy can be used for 3 dimensional tomography or to follow expression and distribution of fluorescently tagged proteins in cells. Like all other commercial AFMs these systems can optionally be used with temperature control, fluid exchange and magnetic tip activation. Please note that the confocal AFM systems can be booked for commercial and academic use.