Dr. Mads Bruun Hovgaard
Research Fellow
Mads Bruun Hovgaard graduated his PhD from the Interdisciplinary NanoScience Center (iNANO), Aarhus University in 2007 based on his work within the field of protein adsorption and aggregation on biocompatible, nano modified metal-oxides. He subsequently continued on at iNANO doing a one year postdoctoral fellowship, focused on a risk assessment of free metal-oxide nanoparticles in a range of biological systems, detailing a characterization and identification of nanoparticles suitable for nanotox test across various biological matrixes. He Joined The Nano Function Group in 2008.
Current Research Interests
M.B.H's research at UCD is pivoted around the topic of amyloid. Key themes include the investigation of nature’s widespread use of functional amyloid for mechanical strength, as well as studies into the interactions between pathogenic amyloid and model lipid membranes. Mads’ core experimental techniques within the Nanoscale Function Group includes AFM liquid imaging, AFM-Force Spectroscopy and Low Noise AFM.
The origin of mechanical properties of curli and csgA amyloid fibrils
In-situ Single molecule interactions between amyloid monomers and lipid model membranes
Publications
Influence of Nanoroughness and Detailed Surface Morphology on Structural Properties and Water-Coupling Capabilities of Surface-Bound Fibrinogen Films, Dolatshahi-Pirouz, A., Skeldal, S., Hovgaard, M. B., Jensen, T., Foss, M., Chevallier, J., and Besenbacher, F., Journal of Physical Chemistry C, 113, 4406-4412, (2009).
Deposition at glancing angle, surface roughness, and protein adsorption: Monte Carlo simulations, Zhdanov, V. P., Rechendorff, K., Hovgaard, M. B., and Besenbacher, F., Journal of Physical Chemistry B, 112, 7267-7272, (2008).
AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon, Mingdong, D., Mads Bruun, H., Wael, M., Sailong, X., Daniel Erik, O., and Flemming, B., Nanotechnology, 384013, (2008).
Fibronectin adsorption on tantalum: The influence of nanoroughness, Hovgaard, M. B., Rechendorff, K., Chevallier, J., Foss, M., and Besenbacher, F., Journal of Physical Chemistry B, 112, 8241-8249, (2008).
Bovine serum albumin adsorption on nano-rough platinum surfaces studied by QCM-D, Dolatshahi-Pirouz, A., Rechendorff, K., Hovgaard, M. B., Foss, M., Chevallier, J., and Besenbacher, F., Colloids and Surfaces B-Biointerfaces, 66, 53-59, (2008).
Scaling behavior of the surface roughness of platinum films grown by oblique angle deposition, Dolatshahi-Pirouz, A., Hovgaard, M. B., Rechendorff, K., Chevallier, J., Foss, M., and Besenbacher, F., Physical Review B, 77, (2008).
Influence of surface roughness on quartz crystal microbalance measurements in liquids, Rechendorff, K., Hovgaard, M. B., Foss, M., and Besenbacher, F., Journal of Applied Physics, 101, (2007).
Quartz crystal microbalance studies of multilayer glucagon fibrillation at the solid-liquid interface, Hovgaard, M. B., Dong, M. D., Otzen, D. E., and Besenbacher, F., Biophysical Journal, 93, 2162-2169, (2007).
Enhancement of protein adsorption induced by surface roughness, Rechendorff, K., Hovgaard, M. B., Foss, M., Zhdanov, V. P., and Besenbacher, F., Langmuir, 22, 10885-10888, (2006).
RNA interference in vitro and in vivo using a chitosan/siRNA nanoparticle system, Howard, K. A., Rahbek, U. L., Liu, X. D., Damgaard, C. K., Glud, S. Z., Andersen, M. O., Hovgaard, M. B., Schmitz, A., Nyengaard, J. R., Besenbacher, F., and Kjems, J., Molecular Therapy, 14, 476-484, (2006).
AFM study of glucagon fibrillation via oligomeric structures resulting in interwoven fibrils, , Dong, M. D., Hovgaard, M. B., Xu, S. L., Otzen, D. E., and Besenbacher, F., Nanotechnology, 17, 4003-4009, (2006).
Nanostructure of the neurocentral growth plate: Insight from scanning small angle X-ray scattering, atomic force microscopy and scanning electron microscopy, Bunger, M. H., Foss, M., Erlacher, K., Hovgaard, M. B., Chevallier, J., Langdahl, B., Bunger, C., Birkedal, H., Besenbacher, F., and Pedersen, J. S., Bone, 39, 530-541, (2006).
Tantalum films with well-controlled roughness grown by oblique incidence deposition, Rechendorff, K., Hovgaard, M. B., Chevallier, J., Foss, M., and Besenbacher, F., Applied Physics Letters, 87, (2005).
Resonant and nonresonant electron impact detachment of CN- and BO, Andersen, L. H., Bak, J., Boye, S., Clausen, M., Hovgaard, M., Jensen, M. J., Lapierre, A., and Seiersen, K., Journal of Chemical Physics, 115, 3566-3570, (2001).
Contact Details
Fax: +353-1-716-6777
Email: madsbruun.hovgaard-at-ucd.ie